It provides to get over doze than standards to increase the chance of treatment and extend a period of deterioration such as at the types of Organ Transplantation, Lymphoma and Leukemia. It means there is deterioration on the place where there is no indicator of Ca. The Cemotherapy, which is sometimes applied overdoses with radiotherapy is almost given more than one or two days. The overdose treatment damages to bone medulla and root cell.
In most disc hernias, a part of exterior fibers of annulus fibrosus had not torn and the disc material is totally within the disc; but, there is diffuse disc protuberance. Although it is less frequent, the cartilaginous tissue bulges out the torn sheath or a free fragment compresses spinal canal and nerve root.
Serious complains have started to be observed following the widespread usage of endoscopic sinus surgeries (ESC) that has been introduced in 1984 for the first time. Since the majority of the encountered problems are determined to be the result of not evaluating the anatomy during the surgery due to various reasons led to the emergence of the need for surgical navigation in ESC.